Nat Clin Pract Rheumatol. 2007;3(1):26-34. Slow transport via folate receptor (lower affinity for methotrexate than for folic acid) Increased drug efflux via ATP-binding cassette (ABC) subfamily ...

Experts say those shortages are often tied to the United States’ heavy reliance on overseas drug manufacturing — a supply ...

Please provide your email address to receive an email when new articles are posted on . “The disease-modifying anti-rheumatic drug methotrexate is the standard-of-care treatment of inflammatory ...

Disease-modifying drug therapies are being sought intensively for osteoarthritis (OA), but none have proved out thus far. A previous trial in patients with OA of the hand had found that methotrexate ...

Methotrexate significantly lowers systolic blood pressure in newly diagnosed RA patients compared to sulfasalazine, potentially reducing cardiovascular risk. The study provides prospective comparative ...

The US Food and Drug Administration (FDA) has approved concomitant use of the biologic pegloticase (Krystexxa) and methotrexate to lower serum uric acid levels (sUA) in patients with chronic gout.

Exploring Pediatric Oncology Care Practices Influencing the Relationships Among Children, Caregivers, and Health Care Providers: A Multi-Institutional Study From Pakistan HD-MTX dosed at 3,000 mg/m 2 ...

Methotrexate is prescribed for psoriasis and certain cancers. It's a generic medication, available as the brand-name drugs Trexall, Xatmep, and more. It comes as an injectable IV solution, ...

A research team, led by Professor Lin Xiang (first right) and Professor Shen Jiangang (second right), has discovered that combining the active ingredient of the Chinese medicine Astragalus ...