AI-designed proteins improved targeted DNA insertion in cultured cells, with one variant doubling the performance of an ...

(Agnes Noy/Catley et al., Nucleic Acids Research, 2026) If you could peer inside a cell's nucleus, you would find DNA tightly ...

A new review argues that oxidized mitochondrial DNA acts as both a persistent inflammatory signal and a potential biomarker ...

Most microscopes can only illuminate objects down to a certain size before tiny features blur together. This blurring is known as the diffraction limit of light. Super-resolution imaging techniques, ...

Metal ions bridging the grooves of two DNA helices explain how they lock together, the first direct look at the DNA zipper ...

In recent years, technologies that allow scientists to study a person's DNA at single-molecule resolution have vastly expanded our knowledge of the human genome, the microbiome, and the genetic basis ...

The newest DNA sequencing technology from Swiss multinational Roche doesn’t measure DNA directly but in fact analyzes a different polymer altogether. The technology is not yet available for sale, but ...

Schematic showing a single DNA duplex bridging two gold electrodes (yellow) patterned on a silicon nitride substrate (green). The setup allows measurement of electrical conductance as metal ions bind ...

Thymine modified polymer for delivering DNA into cells. A thymine modified compound, poly (ethylene glycol) (PEG), is bound to DNA through an annealing process, then delivered by intramuscular ...

Using advanced imaging techniques and precise microfluidics control to stretch out curly DNA into a straight line, new research demonstrates techniques for stretching and immobilizing DNA with minimum ...